3He lung morphometry technique: Accuracy analysis and pulse sequence optimization
نویسندگان
چکیده
منابع مشابه
Quantitative assessment of lung microstructure in healthy mice using an MR-based 3He lung morphometry technique.
The recently developed technique of lung morphometry using hyperpolarized (3)He diffusion magnetic resonance (MR) (Yablonskiy DA, Sukstanskii AL, Woods JC, Gierada DS, Quirk JD, Hogg JC, Cooper JD, Conradi MS. J Appl Physiol 107: 1258-1265, 2009) permits in vivo study of lung microstructure at the alveolar level. Originally proposed for human lungs, it also has the potential to study small anim...
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E. Osmanagic, A. L. Sukstanskii, J. D. Quirk, J. C. Woods, M. S. Conradi, and D. A. Yablonskiy Electrical and Systems Engineering, Washington University, St. Louis, Misssouri, United States, Radiology, Washington University, St. Louis, Missouri, United States, Radiology, Washington University, St. Louis, Misssouri, United States, Physics, Washington University, St. Louis, Missouri, United State...
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Introduction: The lung morphometry technique [1] allows the evaluation of lung microstructure based on an MRI measurement of hyperpolarized He gas diffusion. In this approach, acinar lung airways are considered as cylinders covered by alveolar sleeves [2]. Diffusion of He gas in each airway is anisotropic and described by distinct longitudinal and transverse diffusion coefficients, DL and DT. A...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance
سال: 2010
ISSN: 1090-7807
DOI: 10.1016/j.jmr.2010.09.005